Single-Case Designs

Date: 3 & 10 March 2022
Time: 9.30am - 12.30pm
InstructorDr Suzanne McDonald and Associate Prof Jane Nikles 
Level: Introductory
Fee: £60

Outline

This short course is an introduction to single-case designs (SCD) over two half-day workshops. In the first workshop, we will provide an overview of the different type of SCD and describe some real-world examples of studies using SCD in health research. The second workshop will cover how to evaluate SCD data, focusing on both visual and statistical methods, and conclude with a group activity where attendees design a basic SCD for a clinical scenario

Objectives

On completion of this course, the participants will be able to:

  • Understand single-case design (SCD) methodology and describe some real-world examples of SCDs in health research.
  • Understand the principles of visual and statistical data analysis in SCDs.
  • Be able to design a simple SCD for a clinical scenario and develop a basic analysis plan.

Prerequisites

None.

Recommended reading

  • McDonald, Vieira, & Johnston. "Analysing N-of-1 observational data in health psychology and behavioural medicine: a 10-step SPSS tutorial for beginners." Health psychology and behavioural medicine 8, no. 1 (2020): 32-54.

  • McDonaldQuinnVieiraO'BrienWhite, Johnston& Sniehotta. The state of the art and future opportunities for using longitudinal n-of-1 methods in health behaviour research: a systematic literature overview. Health Psychol Rev 2017 Dec;11(4):307-323.

  • Nikles J, Onghena P, Vlaeyen JW, Wicksell RK, Simons LE, McGree JM, McDonald S. Establishment of an International Collaborative Network for N-of-1 Trials and Single-Case Designs. Contemporary clinical trials communications. 2021 Sep 1;23:100826.

About the instructor

Dr Suzanne McDonald is a clinical researcher and chartered health psychologist with over 10 years of experience in the field of single-case designs. She has applied these designs in various clinical contexts. She has expertise in the statistical analysis of individual SCD data.

Associate Professor Jane Nikles is a registered Medical Practitioner with over 20 years of experience in conducting N-of-1 trials and studies using other types of Single-Case Designs such as Single Case Experimental Designs (SCEDs). She has studied and published extensively about N-of-1 trial design and continues to explore the applications of such trials to optimise patient health outcomes.

Together we represent a world authority on N-of-1 studies, backed by more than 30 years combined experience of research in the field and a global network of clinicians, clinical researchers, and life sciences companies. We are uniquely placed to drive the adoption of this powerful, personalised treatment methodology for Australian patients. We are co-chairs of the International Collaborative Network of N-of-1 trials and Single Case Designs (https://www.nof1sced.org/), a network of nearly 500 researchers, academics, students and clinicians based in 33 countries who are interested in these methods. We have used our expertise to help researchers in Australia and overseas to design their individual and pooled personalised (N-of-1) clinical trials.

Reach us on Twitter: @suzannem5   @nof1sced   @janenikles

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